Chirayu G. Patel, MD, MPH, radiation oncology resident, Vanderbilt University Medical Center, Nashville, Tennessee. Patel will use his seed funding to investigate altered tumor metabolism, particularly tumor reliance on the amino acid glutamine, as a mechanism of radioresistance in non-small cell lung cancer. He will explore if this altered metabolism occurs by increased scavenging of reactive oxygen species and will employ small molecule inhibitors to disrupt glutamine metabolism. Cheng-Chia “Fred” Wu, MD, PhD, radiation oncology resident, NewYork-Presbyterian/Columbia University Medical Center, New York. With his ASTRO grant, Wu will investigate if the integrity of the blood brain barrier limits communication between the central nervous system and the systemic immune systems, namely whether the disruption of the blood brain barrier with focused ultrasound can enhance the effects of checkpoint inhibitor-targeted therapy and the abscopal effect in the brain. All awardees must submit a report to ASTRO at the midterm and the conclusion of their research, and they are strongly encouraged to submit their study as an abstract in a subsequent ASTRO Annual Meeting. The grant winners are selected by ASTRO’s Research Grants Evaluation Committee within the Science Council and approved by the ASTRO Board of Directors. For more information about ASTRO’s grants and awards, visit https://www.astro.org/Funding-Opportunities.aspx . About ASTRO ASTRO is the premier radiation oncology society in the world, with more than 10,000 members who are physicians, nurses, biologists, physicists, radiation therapists, dosimetrists and other health care professionals that specialize in treating patients with radiation therapies.
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